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pentobarbital decreases levels of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Strong CYP3A4 inducers can decrease panobinostat ranges by ~70% and lead to therapy failure.pentobarbital will minimize the level or impact of eletriptan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Mo